Grey's Anatomy Season 21
Created by Shonda Rhimes
The doctors of Grey Sloan Memorial Hospital deal with life-or-death consequences on a daily basis -- it's in one another that they find comfort, friendship and, at times, more than friendship. Together they're discovering that neither medicine nor relationships can be defined in black and white. Real life only comes in shades of grey.
Grey's Anatomy Season 21 has concluded on ABC. It ran from September 26, 2024 to May 15, 2025.
Grey's Anatomy Season 21 has concluded on ABC. It ran from September 26, 2024 to May 15, 2025.
Where to watch in the US
Current US catalog status not verified
The official ABC page may list episodes and access options. Search other services on JustWatch (opens in a new tab)
Release details
Known dates and milestones
Released
ABC
Since Sep 26, 2024
Released
Finale
Since May 15, 2025
Cast and crew
More to watch
About this information
Sources and attribution
Supporting links and attribution for the dates, credits, schedules and watch options shown on this page.
- Official show page
- Season premiere · ABCSeptember 26, 2024Reported
“Grey's Anatomy season 21: September 26, 2024 on ABC”
- Season finale · ABCMay 15, 2025Reported
“Grey's Anatomy season 21 finale: May 15, 2025 on ABC”
- Cast and crew data
- Cast and crew data
- Season release history
Release dates retain the source wording. Season history records original premieres; availability receipts identify options that can be used now or later.
Past changes
Season finale date announced: May 15, 2025 on ABC
Season premiere date announced: September 26, 2024 on ABC