Common Side Effects Season 1
Created by Joe Bennett, Steve Hely
Common Side Effects follows former high school lab partners Marshall and Frances who begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world's diseases.
Common Side Effects Season 1 originally premiered on Adult Swim on February 2, 2025. Current US availability is unconfirmed.
Common Side Effects Season 1 originally premiered on Adult Swim on February 2, 2025. Current US availability is unconfirmed.
Where to watch in the US
Current US availability not verified
It may be available now. Check a broader guide while we verify current catalog options.
Episode guide
Episodes
- 1
Pilot source at TVmaze
In the opening episode, Marshall Cuso shows up in NYC with a mushroom that can cure any disease or injury, and bumps into his old classmate, Frances. But what Marshall doesn't realise is that Frances works for Reutical, a big pharmaceutical company.
- 2
Lakeshore Limited source at TVmaze
Marshall is on the run, trying to flee New York; Frances confides to her boss, Rick, about the mushroom; Rick sends her to Marshall's farm to get more, but the situation gets out of hand.
- 3
Hildy source at TVmaze
Marshall seeks advice from his old mentor, Hildy. Copano and Harrington are drawn further into the mystery of the mushrooms obtained at the raid. Frances has gone to Geneva with her boyfriend Nick (and Rick) but can't resist the call of the mushroom.
- 4
Dumpsite source at TVmaze
Marshall buys a plot of land near a chemical waste site with a plan to grow more mushrooms. Meanwhile, Frances rushes home from Europe after a huge development. Copano and Harrington investigate a connection between Marshall and Frances.
- 5
Star-Tel-Lite source at TVmaze
Frances and Marshall attempt to grow the last of their mushroom supply, hoping their plan works. Copano and Harrington, surveilling Frances and Marshall, run into danger when confronted by a neighboring BMX gang.
- 6
In the System source at TVmaze
Marshall arrives in jail and learns that some very important people refuse to let him out, while danger lurks around every corner. Frances makes a fateful decision. Copano and Harrington pick up the pieces.
- 7
Blowfish source at TVmaze
Marshall is rescued by another inmate, but now Marshall owes him a favor. Desperate to get out of prison, he works on a risky plan when he runs into a surprising ally. Frances grapples with a life-changing event.
- 8
Amelia and Wyatt source at TVmaze
Marshall finds himself in a new circumstance that changes everything, leading him to reunite with an old friend and start a new plan. Frances finds herself torn in the wake of terrible news.
- 9
Cliff's Edge source at TVmaze
Marshall discovers what Hildy has been up to, but obstacles remain. Copano and Harrington zero in on Marshall's location ...
- 10
Raid source at TVmaze
The FBI/DEA raid the compound, resulting in awful consequences. The fate of the mushroom is decided.
Cast and crew
- Produced by
- Benjy Brooke, Greg Daniels, Mike Judge, Steve Hely
About this information
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- Season release history
Release dates retain the source wording. Season history records original premieres; availability receipts identify options that can be used now or later.